Tea, Dub!
نویسندگان
چکیده
منابع مشابه
‘Liminal Dub’ by Gus Cummins
Images from ‘Dub in Liminal [4_TD$DIFF]Space’ produced in 2009–2010 towards MRes Digital Art and Technology at University of Plymouth. I embrace the ‘Dub [7_TD$DIFF]Reggae’ music genre. It strips the language from songs, sometimes returning it in a fragmented form, ornamented with delays and echoes. It provides an analogy for temporal lobe seizures; I experience dub versions of events, with lan...
متن کاملDUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.
Protein ubiquitination is an important regulator of cytokine-activated signal transduction pathways and hematopoietic cell growth. Protein ubiquitination is controlled by the coordinate action of ubiquitin-conjugating enzymes and deubiquitinating enzymes. Recently a novel family of genes encoding growth-regulatory deubiquitinating enzymes (DUB-1 and DUB-2) has been identified. DUBs are immediat...
متن کاملSAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4
Aneuploidy, the unbalanced segregation of chromosomes during cell division, is recurrent in many tumors and the cause of birth defects and genetic diseases. Centromeric chromatin represents the chromosome attachment site to the mitotic spindle, marked by specialized nucleosomes containing a specific histone variant, CEN-H3/Cse4, in yeast. Mislocalization of Cse4 outside the centromere is delete...
متن کاملExtended ubiquitin species are protein-based DUB inhibitors
A frameshift mutation in the transcript of the ubiquitin-B gene leads to a C-terminally extended ubiquitin (Ub), UBB(+1). UBB(+1) has been considered to inhibit proteasomes and as such to be the underlying cause for toxic protein buildup correlated with certain neuropathological conditions. We demonstrate that expression of extended Ub variants leads to accumulation of heterogeneously linked po...
متن کاملDUB-1, a deubiquitinating enzyme with growth-suppressing activity.
Cytokines regulate cell growth by inducing the expression of specific target genes. Using the differential display method, we have cloned a cytokine-inducible immediate early gene, DUB-1 (for deubiquitinating enzyme). DUB-1 is related to members of the UBP superfamily of deubiquitinating enzymes, which includes the oncoprotein Tre-2. A glutathione S-transferase-DUB-1 fusion protein cleaved ubiq...
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ژورنال
عنوان ژورنال: James Joyce Quarterly
سال: 2006
ISSN: 1938-6036
DOI: 10.1353/jjq.2007.0014